Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p220 | (1) | WCRB2014

Crosstalk of TGFβ superfamily with Smad1 in testis

Chan Kai-Hui , Galuska Sebastian P , Loveland Kate L , Lutz Konrad

The TGFβ superfamily consists of more than 30 ligands, which exert their multiple functions during early embryonic development and in adult tissues. During spermatogenesis, several TGFβ superfamily ligands are present simultaneously to regulate critical stages of development through shared receptors and overlapping transduction molecules. However, the understanding of this promiscuity of signalling pathways remains unfortunately incomplete. Our aim is to study the me...